tert-butyl (5-broMo-2-pyriMidinyl)carbaMate
tert-butyl (5-bromopyrimidin-2-yl)carbamate
CAS: 883231-23-0
Molecular Formula: C9H12BrN3O2
tert-butyl (5-broMo-2-pyriMidinyl)carbaMate - Names and Identifiers
| Name | tert-butyl (5-bromopyrimidin-2-yl)carbamate |
| Synonyms | 5-Bromo-N-Boc-pyrimidin-2-amine N-Boc-2-AMino-5-broMopyriMidine 2-(N-BOC-Amino)-5-bromopyrimidine (5-Bromopyrimidin-2-yl)tert-butylcarbamate tert-butyl (5-broMo-2-pyriMidinyl)carbaMate tert-Butyl (5-bromopyrimidin-2-yl)carbamate tert-butyl (5-bromopyrimidin-2-yl)carbamate (5-Bromo-pyrimidin-2-yl)-carbamic acid tert-butyl ester |
| CAS | 883231-23-0 |
| InChI | InChI=1/C9H12BrN3O2/c1-9(2,3)15-8(14)13-7-11-4-6(10)5-12-7/h4-5H,1-3H3,(H,11,12,13,14) |
tert-butyl (5-broMo-2-pyriMidinyl)carbaMate - Physico-chemical Properties
| Molecular Formula | C9H12BrN3O2 |
| Molar Mass | 274.11 |
| Density | 1.513±0.06 g/cm3(Predicted) |
| pKa | 10.38±0.70(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
| Refractive Index | 1.576 |
tert-butyl (5-broMo-2-pyriMidinyl)carbaMate - Introduction
tert-butyl (5-bromopyrimidin-2-yl)carbamate is an organic compound containing a Boc protecting group (tert-butoxycarbonyl) and a bromopyrimidine ring in its chemical structure.
Nature:
-Appearance: Colorless to light yellow solid
-melting point: about 140-144 ℃
-Solubility: Soluble in organic solvents such as methanol, ethanol and dichloromethane
Use:
- tert-butyl (5-bromopyrimidin-2-yl)carbamate can be used as an intermediate in organic synthesis and used in the synthesis of other compounds.
-can be used to synthesize drugs, pesticides, photosensitizers and other organic compounds.
Preparation Method:
The preparation of tert-butyl (5-bromopyrimidin-2-yl)carbamate usually uses the following steps:
1. 5-bromopyrimidine was reacted with tri-tert-butoxycarbonyl amine to obtain tert-butyl (5-bromopyrimidin-2-yl)carbamate.
Safety Information:
- tert-butyl (5-bromopyrimidin-2-yl)carbamate has limited toxicity data, but it is usually necessary to take appropriate precautions when working in the laboratory, such as wearing gloves and safety glasses.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
-This compound is potentially irritating and allergenic and should be handled with caution and stored properly. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Nature:
-Appearance: Colorless to light yellow solid
-melting point: about 140-144 ℃
-Solubility: Soluble in organic solvents such as methanol, ethanol and dichloromethane
Use:
- tert-butyl (5-bromopyrimidin-2-yl)carbamate can be used as an intermediate in organic synthesis and used in the synthesis of other compounds.
-can be used to synthesize drugs, pesticides, photosensitizers and other organic compounds.
Preparation Method:
The preparation of tert-butyl (5-bromopyrimidin-2-yl)carbamate usually uses the following steps:
1. 5-bromopyrimidine was reacted with tri-tert-butoxycarbonyl amine to obtain tert-butyl (5-bromopyrimidin-2-yl)carbamate.
Safety Information:
- tert-butyl (5-bromopyrimidin-2-yl)carbamate has limited toxicity data, but it is usually necessary to take appropriate precautions when working in the laboratory, such as wearing gloves and safety glasses.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
-This compound is potentially irritating and allergenic and should be handled with caution and stored properly. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:18:00
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View History
tert-butyl (5-broMo-2-pyriMidinyl)carbaMate
4-Chloropyrido[3,2-d]pyri...
Zinc bis(monohexadecyl maleate)
1,2-双(二甲硅基)苯
Cyclopropyl bronic acid pinacle ester
甲基 6-O-[(叔丁基)二甲基硅烷基]-ALPHA-D-吡喃甘露糖苷三苯甲酸酯
Z-O-T-BUTYL-TYROSINE ETHYL ESTER
TYPHANEOSIDE 香蒲新苷
(4-氰基苯基)三氟硼酸钾
POTASSIUM OCTOXYNOL-12 PHOSPHATE
4-Chloropyrido[3,2-d]pyri...
Zinc bis(monohexadecyl maleate)
1,2-双(二甲硅基)苯
Cyclopropyl bronic acid pinacle ester
甲基 6-O-[(叔丁基)二甲基硅烷基]-ALPHA-D-吡喃甘露糖苷三苯甲酸酯
Z-O-T-BUTYL-TYROSINE ETHYL ESTER
TYPHANEOSIDE 香蒲新苷
(4-氰基苯基)三氟硼酸钾
POTASSIUM OCTOXYNOL-12 PHOSPHATE